Table 2.
Baseline characteristics of the LTHT cohort
| Characteristic | Total N (%) |
No cirrhosis N (%) |
Cirrhosis N (%) |
P value |
| 289 | 98 (33.9%) | 191 (66.1%) | ||
| Age group | ||||
| <50 | 22 (7.6) | 10 (10.2) | 12 (6.3) | 0.26 |
| 50–59 | 49 (17.0) | 10 (10.2) | 39 (20.4) | 0.04 |
| 60–69 | 81 (28.0) | 18 (18.4) | 63 (33.0) | 0.03 |
| 70–79 | 92 (31.8) | 31 (31.6) | 61 (31.9) | 0.95 |
| 80+ | 45 (15.6) | 29 (29.6) | 16 (8.4) | <0.001 |
| Sex | ||||
| Male | 228 (78.0) | 76 (77.6) | 152 (79.6) | 0.83 |
| Female | 61 (21.1) | 22 (22.4) | 39 (20.4) | 0.73 |
| Ethnicity | ||||
| White | 252 (87.1) | 87 (88.8) | 165 (86.4) | 0.86 |
| Black | 12 (4.2) | 5 (5.1) | 7 (3.7) | 0.58 |
| South Asian | 12 (4.2) | 2 (2.0) | 10 (5.2) | 0.21 |
| Chinese | 4 (1.4) | 0 | 4 (2.1) | 0.15 |
| Other Ethnic group | 4 (1.4) | 1 (1.0) | 3 (1.6) | 0.70 |
| Not stated | 5 (1.7) | 3 (3.1) | 2 (1.0) | 0.22 |
| Aetiology | ||||
| HCV | 44 (15.2) | 4 (4.1) | 40 (20.9) | <0.001 |
| HBV | 17 (5.9) | 5 (5.1) | 12 (6.3) | 0.69 |
| PBC | 7 (2.4) | 0 | 7 (3.7) | 0.06 |
| AIH | 3 (1.0) | 0 | 3 (1.6) | 0.21 |
| Haemochromatosis | 19 (6.6) | 5 (5.1) | 14 (7.3) | 0.48 |
| Alcohol | 68 (23.5) | 4 (4.1) | 64 (33.5) | <0.001 |
| NAFLD | 43 (14.9) | 13 (13.3) | 30 (15.7) | 0.60 |
| Other/unknown | 88 (30.4) | 67 (68.4) | 21 (11.0) | <0.001 |
| MELD | ||||
| <10 | 90 (47.1) | |||
| 10–14 | 73 (38.2) | |||
| 15–19 | 21 (11.0) | |||
| 20+ | 7 (3.7) | |||
| Child-Pugh | ||||
| A | 131 (68.6) | |||
| B | 44 (23.0) | |||
| C | 16 (8.4) | |||
| Previous decompensation | ||||
| Ascites | 37 (19.3) | |||
| Variceal bleed | 13 (6.8) |
AIH, autoimmune hepatitis; HBV, hepatitis B virus; HCV, hepatitis C virus; LTHT, Leeds Teaching Hospitals NHS Trust; MELD, Model for End-Stage Liver Disease; NAFLD, non-alcoholic fatty liver disease; PBC, primary biliary cirrhosis.