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. 2019 Jul 9;9(7):e028571. doi: 10.1136/bmjopen-2018-028571

Table 4.

Performance of different published algorithms for cirrhosis detection in the LTHT cohort of patients with HCC

Algorithm Sensitivity (%) 95% CI Specificity (%) 95% CI PPV (%) 95% CI
Lower Upper Lower Upper Lower Upper
Kramer et al 7 72 67 77 100 100 100 100 100 100
Jepsen et al 8 71 66 76 100 100 100 100 100 100
Nehra et al 9 80 76 85 98 96 100 99 97 100
Ratib et al 15 80 76 85 98 96 100 99 97 100
Algorithm 4 86 82 90 98 96 100 99 97 100

HCC, hepatocellular carcinoma; LTHT, Leeds Teaching Hospitals NHS Trust; PPV, positive predictive value.