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. 2019 Jul 10;9(7):e024377. doi: 10.1136/bmjopen-2018-024377

Table 4.

Type and frequency of the causes of DRP in medicines associated with high risk of DRP in neonatal intensive care

Medicines Causes of DRP*
Drug selection Dose selection Drug use process Logistics Others†
Amphotericin B 7 (15.2%) 21 (45.7%) 11 (23.9%) 7 (15.2%)
Meropenem 1 (1.0%) 38 (38.0%) 25 (25.0%) 29 (29.0%) 7 (7.0%)
Alprostadil 2 (12.5%) 6 (37.5%) 8 (50.0%)
Vancomycin 1 (1.0%) 28 (28.9%) 24 (24.74%) 40 (41.24%) 4 (4.12%)
Ciprofloxacin 3 (23.08%) 4 (30.77%) 2 (15.38%) 4 (30.77%)
Gentamicin 132 (62.6%) 73 (34.6%) 4 (1.9%) 2 (0.9%)
Cefepime 16 (42.1%) 10 (26.32%) 11 (28.95%) 1 (2.63%)
Amikacin 47 (64.4%) 14 (19.2%) 8 (10.9%) 4 (5.5%)
Omeprazole 1 (3.57%) 15 (53.57%) 12 (42.86%)

*Causes of DRP according to the Pharmaceutical Care Network Europe classification system V.6.2.4

†Others included drug form, treatment duration and other specific causes (eg, adverse reaction and wrong drug preparation technique).

DRP, drug-related problem.