Table 2. Presence of groups 1–13 grass pollen allergens in pollen of different grass species as determined by cloning, specific antisera/antibodies and IgE-binding/inhibition experiments.
Allergens | MW | Phl p | Poa p | Lol p | Dac g | Fes p | Ant o | Ave s | Hol l | Sec c | Pas n | Zea m | Cyn d | Phr a | Ory s |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Allergens found in all grasses | |||||||||||||||
Group 1 | 31–35 kDa | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Group 13 | ~55 kDa | + | + | + | + | + | + | + | + | + | + | + | + | + | ± |
Allergens found in some grasses | |||||||||||||||
Group 2/3 | 10–12 kDa | + | + | + | + | − | + | + | + | + | n.d. | − | − | − | ± |
Group 5 | 27–33 kDa | + | + | + | + | + | + | + | + | + | n.d. | − | − | + | − |
Group 6 | ~13 kDa | + | + | − | − | − | + | − | − | − | n.d. | − | − | − | − |
Group 11 | ~20 kDa | + | n.d. | + | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | + | n.d. | n.d. | + |
Allergens, not grass-specific | |||||||||||||||
Group 4 | 50–67 kDa | + | + | + | + | + | + | + | + | + | n.d. | + | + | + | n.d. |
Group 7 | ~9 kDa | + | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | n.d. | + | n.d. | + |
Group 12 | ~14 kDa | + | + | + | n.d. | n.d. | + | + | n.d. | + | n.d. | + | + | + | + |
MW, molecular weight; +, allergen cloned or found by specific antiserum/antibody probe or IgE-binding/inhibition experiment; −, allergen not cloned or found by specific antiserum/antibody probe or IgE-binding/inhibition experiment; ±, presence of allergen predicted by in silico sequence analysis; n.d., no data. Phl p, Phleum pratense; Poa p, Poa pratensis; Lol p, Lolium perenne; Dac g, Dactylis glomerata; Fes p, Festuca pratensis; Ant o, Anthoxantum odoratum; Ave s, Avena sativa; Hol l, Holcus lanatus; Sec c, Secale cereale; Pas n, Paspalum notatum; Zea m, Zea mays; Cyn d, Cynodon dactylon; Phr a, Phragmites australis; Ory s, Oryza sativa.