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. Author manuscript; available in PMC: 2020 May 9.
Published in final edited form as: J Med Chem. 2019 Apr 30;62(9):4669–4682. doi: 10.1021/acs.jmedchem.9b00274

Figure 3.

Figure 3.

Chemoselectivity of the Chan-Lam coupling reaction. Under reaction conditions, the arylation occurred exclusively at the N-3 site to yield subtype 12 with O-arylated products 11 not observed.