Percentage of elements in clusters carrying specific epigenetic mark STARR-seq enhancers (A), DHS-predicted enhancers (B), and non-enhancer DHSs (C) were clustered into eight groups. The percentage of elements carrying the corresponding mark was calculated and shown as red bar within each cluster. A cluster is designated to be absent of an epigenetic mark if ≤10% of the elements in that cluster carrying the epigenetic mark examined, or designated as low, medium, or high if the percentage of elements in a specific cluster carrying an epigenetic mark examined between 10%–30%, 30%–60%, and >60%.