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. 2019 Jul 11;9:10078. doi: 10.1038/s41598-019-45245-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Serum XPNPEP2 levels in normal and prostate cancer patients. Western blot assay clarified secreted XPNPEP2 in serums of Pca patients (A). The ELISA assay detected serum XPNPEP2 levels in normal, BPH and Pca patients using a human XPNPEP2 ELISA pair set, the scatter plots were showed (B). (C) Plots illustrated the serum XPNPEP2 levels in Pca patients with local invasion versus without local invasion. (D) Plots showing the serum XPNPEP2 levels in Pca patients with LN metastasis versus without LN metastasis.