Skip to main content
. 2019 Jun 28;6:645–655. doi: 10.1016/j.toxrep.2019.06.016

Table 1.

The route of administration and doses administered for the three sulfonates.

Chemical
Administered
Route Dose
(mg/kg)
Dose
(mmol/kg)
Time points of blood collection
KPFBS IV 4 0.0118 0.083, 0.25, 0.5, 0.75, 1, 1.5, 3, 6, 12, 24, 48 hrs (M & F)
Gavage 4 0.0118 0.083, 0.25, 0.5, 0.75, 1, 1.5, 3, 6, 9, 12, 24, 48 hrs (M & F)
20 0.0591
100 0.2957
PFHxSK IV 4 0.0091 0.083, 0.25, 0.5, 1, 3, 6, 12, 24, 192, 528, 864, 1200 hrs (M)
0.083, 0.25, 0.5, 1, 3, 6, 12, 24, 48, 96, 192, 288, 528 hrs (F)
Gavage 4 0.0091 0.25, 1, 3, 6, 12, 24, 192, 528, 864, 1200 hrs (M)
0.25, 1, 3, 6, 12, 24, 48, 96, 192, 288, 528 hrs (F)
16 0.0365
32 0.0730
PFOS IV 2 0.004 0.083, 1, 6, 12, 24, 192, 528, 864, 1200 hrs, 11, 15, 20 wks (M & F)
Gavage 2 0.004 0.083, 1, 6, 12, 24, 192, 528, 864, 1200 hrs, 11, 15, 20 wks (M & F)
2 (x 5)a 0.020b
20 0.040

a Dose administered for 5 days.

b Total dose administered.