Table 1.
Chemical Administered |
Route | Dose (mg/kg) |
Dose (mmol/kg) |
Time points of blood collection |
---|---|---|---|---|
KPFBS | IV | 4 | 0.0118 | 0.083, 0.25, 0.5, 0.75, 1, 1.5, 3, 6, 12, 24, 48 hrs (M & F) |
Gavage | 4 | 0.0118 | 0.083, 0.25, 0.5, 0.75, 1, 1.5, 3, 6, 9, 12, 24, 48 hrs (M & F) | |
20 | 0.0591 | |||
100 | 0.2957 | |||
PFHxSK | IV | 4 | 0.0091 | 0.083, 0.25, 0.5, 1, 3, 6, 12, 24, 192, 528, 864, 1200 hrs (M) 0.083, 0.25, 0.5, 1, 3, 6, 12, 24, 48, 96, 192, 288, 528 hrs (F) |
Gavage | 4 | 0.0091 | 0.25, 1, 3, 6, 12, 24, 192, 528, 864, 1200 hrs (M) 0.25, 1, 3, 6, 12, 24, 48, 96, 192, 288, 528 hrs (F) |
|
16 | 0.0365 | |||
32 | 0.0730 | |||
PFOS | IV | 2 | 0.004 | 0.083, 1, 6, 12, 24, 192, 528, 864, 1200 hrs, 11, 15, 20 wks (M & F) |
Gavage | 2 | 0.004 | 0.083, 1, 6, 12, 24, 192, 528, 864, 1200 hrs, 11, 15, 20 wks (M & F) | |
2 (x 5)a | 0.020b | |||
20 | 0.040 |
a Dose administered for 5 days.
b Total dose administered.