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. 2019 Jul 11;10(7):531. doi: 10.1038/s41419-019-1764-1

Fig. 8. cPLA2 inhibition attenuates spinal cord ventral horn neuronal cell death in mice after SCI.

Fig. 8

a–c Expression of cleavage (145–150 kDa) and full length (240 kDa) of α-fodrin in sham and injured spinal cords at 24 h after SCI. Western blot data demonstrating decreased cleavage of α-fodrin in AACOCF3 (AA)-treated as compared with vehicle treated SCI mice. N = 6 mice/group. d Images (20×) demonstrating decreased cell death (TUNEL) in spinal cord sections from SCI/AACOCF3 as compared with SCI/Veh. Scale bar = 100 μm. e Quantification of TUNEL positive cells. N = 6 (Sham/Veh), 6 (Sham/AA), 5(SCI/Veh), and 6 (SCI/AA). Data are mean ± SEM, Two-way ANOVA with Bonferroni posttests, **p < 0.01, ***p < 0.001 versus Sham/Veh, #p < 0.05, ##p < 0.01 versus SCI/Veh