Table 3.
Multivariable regression model for prediction of cardiac mortality based on the derivation cohort.
| In-hospital cardiac mortality | 30-day cardiac mortality | 1-year cardiac mortality | ||||
|---|---|---|---|---|---|---|
| Odds Ratio (95%CI) | P | Odds Ratio (95%CI) | P | Odds Ratio (95%CI) | P | |
| Age (years) | <0.001 | <0.001 | <0.001 | |||
| <40 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| 40–59 | 4.26 (0.58–31.41) | 2.91 (0.70–12.16) | 3.84 (0.93–15.93) | |||
| 60–69 | 5.92 (0.80–44.08) | 3.42 (0.81–14.48) | 5.55 (1.33–23.20) | |||
| 70–79 | 9.46 (1.26–70.99) | 5.94 (1.39–25.39) | 9.57 (2.27–40.33) | |||
| > = 80 | 18.48 (2.44–140.17) | 10.71 (2.47–46.46) | 17.26 (4.04–73.63) | |||
| Gender | Not significant | Not significant | Not significant | |||
| Male | ||||||
| Female | ||||||
| History of diabetes | Not significant | Not significant | 0.014 | |||
| No | 1.00 (reference) | |||||
| Yes | 1.33 (1.06–1.67) | |||||
| History of hypertension | Not significant | Not significant | Not significant | |||
| No | ||||||
| Yes | ||||||
| History of dyslipidemia | NA | NA | Not significant | |||
| No | ||||||
| Yes | ||||||
| History of IHD | 0.001 | 0.006 | Not significant | |||
| No | 1.00 (reference) | 1.00 (reference) | ||||
| Yes | 0.55 (0.38–0.80) | 0.62 (0.44–0.87) | ||||
| Current smoker | Not significant | Not significant | Not significant | |||
| No | ||||||
| Yes | ||||||
|
BMI (kg/m2) < = 23 >23 |
Not significant | Not significant | Not significant | |||
| Killip class on admission | <0.001 | <0.001 | <0.001 | |||
| I | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| II | 1.07 (0.59–1.93) | 1.20 (0.71–2.03) | 1.13 (0.73–1.76) | |||
| III | 2.77 (1.79–4.31) | 2.70 (1.79–4.09) | 2.42 (1.68–3.48) | |||
| IV | 4.24 (3.11–5.77) | 3.75 (2.79–5.05) | 3.27 (2.50–4.27) | |||
| Cardiac arrest in ambulance/on admission | <0.001 | <0.001 | <0.001 | |||
| No | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Yes | 6.61 (4.52–9.65) | 5.09 (3.52–7.37) | 4.55 (3.20–6.46) | |||
| Anterior STEMI | Not significant | Not significant | Not significant | |||
| No | ||||||
| Yes | ||||||
| Creatinine on admission (µmol/L) | <0.001 | <0.001 | <0.001 | |||
| <70 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| 70–105 | 1.26 (0.73–2.16) | 1.19 (0.73–1.95) | 1.11 (0.75–1.64) | |||
| 106–140 | 2.36 (1.36–4.09) | 2.29 (1.39–3.77) | 1.92 (1.28–2.89) | |||
| 141–176 | 3.74 (2.01–6.96) | 3.16 (1.77–5.62) | 2.55 (1.57–4.13) | |||
| 177–353 | 5.04 (2.67–9.52) | 4.08 (2.26–7.38) | 3.25 (1.97–5.38) | |||
| > = 354 | 4.37 (1.97–9.70) | 2.94 (1.36–6.38) | 3.79 (2.05–6.99) | |||
| Hemoglobin on admission (g/dL) | <0.001 | 0.001 | <0.001 | |||
| <10 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| 10–11 | 1.94 (1.05–3.59) | 1.57 (0.88–2.80) | 1.47 (0.87–2.46) | |||
| 12–13 | 1.13 (0.62–2.06) | 0.87 (0.50–1.53) | 0.96 (0.59–1.59) | |||
| 14–16 | 0.73 (0.39–1.35) | 0.59 (0.33–1.05) | 0.67 (0.40–1.12) | |||
| > = 17 | 0.77 (0.38–1.56) | 0.81 (0.43–1.54) | 0.89 (0.50–1.57) | |||
| Elevated first troponin T/I on admission | <0.001 | <0.001 | <0.001 | |||
| No | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Yes | 1.69 (1.27–2.25) | 1.76 (1.35–2.30) | 1.68 (1.34–2.12) | |||
|
S2B (minutes) < = 180 >180 |
Not significant | Not significant | Not significant | |||
| Lowest LVEF during hospitalization (%) | <0.001 | <0.001 | <0.001 | |||
| <40 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| 40–50 | 0.21 (0.15–0.30) | 0.24 (0.18–0.33) | 0.25 (0.19–0.32) | |||
| >50 | 0.25 (0.16–0.38) | 0.22 (0.14–0.34) | 0.27 (0.19–0.37) | |||
CI: confidence interval; IHD: ischemic heart disease; BMI: body mass index; STEMI: ST-segment elevation myocardial infarction; S2B: symptom-to-balloon; LVEF: left ventricular ejection fraction; NA: not applicable.