Table 2. Grading of PDAC [adapted from (13)].

Criteria	G1	G2	G3
Architecture	Tubular, middle-sized duct-like structures, papillary projections	Middle and small-sized duct-like structures, cribriform structures	Solid areas, budding, single cell infiltration
Cells	Cylindrical, retained mucin	Cubic, partial loss of mucin	Polygonal, pleomorphic, spindle, loss of mucin production
Nuclei	Slightly polymorphous	Moderately polymorphous	Very polymorphous
Mitoses	1–5/10 HPF	6–10/10 HPF	>10/10 HPF

PDAC, pancreatic ductal adenocarcinoma.