Table 1.
Basal gene expression in the livers of AhR-KO mice as compared to the control AhR.
| Accession no. | Symbol | Gene name | z-score |
|---|---|---|---|
| Ubiquitin and ubiquitin like system | |||
| NM_009455 | Ube2e1 | Ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog (yeast) | −3.106235 |
| NM_009993 | Ube2l3 | Ubiquitin-conjugating enzyme E2L 3 | −6.65791 |
| NM_012012 | Ube3a | Ubiquitin-protein ligase E3A | −5.227039 |
| AK018743 | Pias2 | Protein inhibitor of activated STAT 2 | −2.709916 |
| AK005791 | SYVN1 | Synovial apoptosis inhibitor 1, synoviolin | −2.131618 |
| NM_024477 | Anapc5 | Anaphase-promoting complex subunit 5 | −1.702395 |
| Proteosome | |||
| NM_026519 | Psmd12 | Proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | −3.34548 |
| NM_013875 | Psmb3 | Proteasome (prosome, macropain) subunit, beta type 3 | −2.09799 |
| NM_013873 | Psmb2 | Proteasome (prosome, macropain) subunit, beta type 2 | −2.62315 |
| Metabolism of xenobiotics by cytochrome P450 - Mus musculus (mouse) | |||
| Fase I | |||
| NM_010750 | Cyplal | Cytochrome P450, family 1, subfamily a, polypeptide 1 | −2.248441 |
| NM_010759 | Cyp1a2 | Cytochrome P450, family 1, subfamily a, polypeptide 2 | −1.873759 |
| NM_023371 | Cyp2e1 | Cytochrome P450, family 2, subfamily e, polypeptide 1 | −1.854343 |
| FaseII | |||
| NM_008487 | Gstm2 | Glutathione S-transferase, mu 2 | −2.585971 |
| NM_008510 | Gsttl | Glutathione S-transferase, theta 1 | −3.387056 |
| Glycolysis/gluconeogenesis | |||
| NM_016859 | Hk2 | Hexokinase 2 | −1.546956 |
| NM_021396 | Pfkp | Phosphofructokinase, platelet | −1.673929 |
| NM_020007 | Pgam2 | Phosphoglycerate mutase 2 | −1.504628 |