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. 2019 Jul 5;10:735. doi: 10.3389/fphar.2019.00735

Figure 1.

Figure 1

Changes of echocardiographic characterization of cardiac function in myocardial ischemia–reperfusion injury (MIRI) mice. After 30 min of ischemia and 18 h of reperfusion, the effect of ginkgo flavonol glycosides (GFGs, 2.5 ml/kg), ginkgolides (GGs, 2.5 ml/kg), and Shuxuening injection (SXNI, 2.5 ml/kg) on cardiac function was quantitatively ▲ evaluated. (A) Representative echocardiography images of different groups. Bar graph quantitation of echocardiographic changes in cardiac function in different groups detected in M-mode: (B) LVEF %, (C) LVFS %, (D) CO, (E) stroke volume, (F) LVIDd, (G) LVIDs, (H) LVPWd, (I) LVPWs, (J) LV Vold, (K) LV Vols, (L) heart rate, and (M) LV mass. Values were expressed as mean ± SEM (n = 5). ## P < 0.01 vs. sham group, *P < 0.05, **P < 0.01 vs. I/R group, ▲ P < 0.05, ▲▲ P < 0.01 vs. GFGs group (LV, left ventricular; EF, ejection fraction; FS, LV fractional shortening; CO, cardiac output; LVIDd, LV internal dimensions at diastole; LVIDs, LV internal diameter systole; LVPWd, LV posterior wall diastole; LVPWs, LV posterior wall systole; LV Vols, LV systole volume; LV Vold, LV diastole volume).