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. 2019 Jul 5;10:735. doi: 10.3389/fphar.2019.00735

Figure 3.

Figure 3

GFGs and GGs alleviated the myocardial I/R injury in MIRI mice. After 30 min of ischemia and 24 h of reperfusion, the protective effects of GFGs and GGs on MIRI were assessed by hematoxylin and eosin staining and measurement of biochemical parameters. (A) Hematoxylin and eosin staining results for the histopathological of the myocardial tissue indicated the histopathological changes in I/R model as well as that caused by GFGs, GGs, and SXNI. Myocardium damage sections were observed and indicated with yellow arrows in representative pictures (12.5×, 100×, and 400× magnification). (B–E) Effects of GFGs and GGs on the alterations of lactate dehydrogenase (LDH), aspartate aminotransferase (AST), creatine kinase-MB (CK-MB), and creatine kinase (CK) in serum following reperfusion (n = 6). Values were expressed as mean ± SEM. # P < 0.05, ## P < 0.01 vs. sham group, *P < 0.05, **P < 0.01 vs. I/R group, ▲ P < 0.05 vs. GFGs group.