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. 2019 Jul 12;20:388. doi: 10.1186/s12859-019-2977-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Data visualization and cell-type clustering before and after imputing the MCA data. a t-SNE visualization of the original uterus tissue data labeled by cell type. b t-SNE after dropout c t-SNE after application of RESCUE. d t-SNE after application of scImpute. e t-SNE after application of DrImpute. f The percent improvement after imputation over the data containing dropout in similarity measures between known cell types and clustering results for all four tissue types