Table 1.
Test characteristics | Sensitivity | Specificity | Reference |
---|---|---|---|
Standard of care | 0.35 | 0.65 | Expert Opinion [16, 17] |
FIB-4 (cut off 1.30) | 0.84 | 0.74 | [18, 19] |
FIB-4 (cut off 3.25) | 0.38 | 0.97 | [18, 19] |
ELF | 0.80 | 0.90 | [19, 20] |
Fibroscan | 0.82 | 0.84 | [19, 21] |
Population and disease characteristics | Transition probability | ||
Prevalence of advanced fibrosis in the general population | 0.075 | [5] |
Published test characteristics of non-invasive liver fibrosis tests to detect advanced fibrosis (METAVIR ≥F3) in patients with non-alcoholic fatty liver disease