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. 2019 Jul 11;14:123. doi: 10.1186/s13014-019-1295-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Left: cross-section of schematic for the 96-well plate geometry and composition in FLUKA MC for experiment A and B. Right: central line profile through physically optimized SOBP plan for experiment B, displaying both physical dose and LET_d. The biological measurement positions are designated by the highlighted regions (p1, p2, p3, p4)