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. 2019 Jul 12;7:179. doi: 10.1186/s40425-019-0656-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Correlations between the CEA level, number of monocytes, LMR, ApoA1 and density of immune cells in the tumor microenvironment. a The density of CD8+ T cells in the core of the tumor showed a tendency that correlated with the level of CEA in the blood, with a coefficient of − 0.135 (P = 0.037). b The density of CD3+ T cells in the core of the tumor was significantly related to the LMR, with a coefficient of 0.135 (P = 0.038). c The density of CD3+ T cells in the core of the tumor showed a tendency that correlated with the number of monocytes in the blood, with a coefficient of − 0.127 (P = 0.052). d The densities of CD3+ T cells in the core of the tumor showed a tendency that correlated with ApoA1, with a coefficient of 0.127 (P = 0.051). e The densities of CD3+ T cells in the invasive margin were correlated with ApoA1, with a coefficient of 0.169 (P = 0.010)