Table 3.

Association between tumor markers and immune cells in the microenvironment

Variable	CD3+ T cells in the CT			CD3+ T cells in the IM			CD8+ T cells in the CT				CD8+ T cells in the IM			Immunoscore
	Low	High	P	Low	High	P	Low	High	P		Low	High	P	Low	High	P
CEA	11.00 (0.39–12,257.00)	10.30 (0.56–3704.00)	0.593	12.21 (0.39–12,257.00)	8.53 (0.56–3704.00)	0.120	12.53 (0.56–3704.00)	7.89 (0.39–12,257.00)	0.064		10.54 (0.39–9064)	10.42 (0.56–12,257.00)	0.983	11.34 (0.39–12,257.00)	10.14 (0.56–3704.00)	0.295
CA 19–9	26.01 (0.60–18,707.00)	32.60 (0.60–20,000.00)	0.145	28.29 (0.60–18,707.00)	29.47 (0.60–20,000.00)	0.861	29.97 (0.60–20,000.00)	27.64 (0.60–18,707.00)	0.378		30.35 (0.60–5956.00)	27.64 (0.60–20,000.00)	0.993	28.43 (0.60–18,707.00)	30.33 (0.60–20,000.00)	0.544

CA 19–9 carbohydrate antigen 19–9, CEA carcinoembryonic antigen, CT core of the tumor, IM invasive margin