Table 3.
Data generated by proposed outcome measures at baseline and follow-up
| Measure | Baseline | Follow-up |
|---|---|---|
|
STOPP mean (per patient) (range) SD# Median (IQR) |
3.27 (0–7) 1.96 3.0 (2.0–4.25) |
2.54 (0–5) 1.24, 2.0 (2.0–3.25) |
|
START mean (per patient) (range) SD# Median (IQR) |
2.35 (0–6)1.42 2 (1–3) |
2.05 (0–6) 1.55 2.0 (1.0–3.0) |
| *Falls in past 3 months (total number) | 12 | 10 |
| Falls in past 3 months (number of patients falling) | 9/40 (20%) | 7/40 (17.5%) |
|
Falls per person (mean (range) SD) Median (IQR) |
0.33 (0–3) 0.694 0.0 (0–0) |
0.25 (0–2) 0.588 0.0 (0–0) |
|
Barthel mean (range) SD Median (IQR) |
6.53 (0–17) 5.50 6.5 (1–9) |
6.38 (0–19) 5.51 6.0 (1.0–10.0) |
|
***MMSE mean (range) SD Median (IQR) Number |
20.13 (9–30) 7.03 21.0 (14.25–25.5) (n = 16) |
20.79 (11–29) 5.90 20.5 (15–26) (n = 14) |
| Drug burden index (DBI) score 0 (n (%)) | 14 (35%) | 14 (35%) |
|
**Drug burden index (DBI) N score > 0 (n (%)) Mean (range) SD Median (IQR) |
26 (65%) 1.11 (0.14–3.37) 0.74 1.035 (0.5–1.5) |
26 (65%) 0.93 (0.14–3.34) 0.67 0.76 (0.5–1.17 |
|
Number of medicines per patient mean (range) SD) Median (IQR) (includes topical preparations) |
9.3 (1–26) 5.9 8.5 (6–12) |
8.7 (0–31) 6.0 8 (5–10) |
|
Total Qualidem mean, (range) SD, Median, (IQR) |
93 (67–130) 15.55 91.0 (79.25–101.5) |
77.85 (31–109) 18.32 79.0 (71.0–92.5) |
|
a. Care relationship (mean (range) SD, Median (IQR) |
15.33 (10–23) 3.53 14.0 (12.25–18.0) |
15.83 (4–21) 5.00 16.0 (13.0–20.0) |
|
b. Positive Affect mean (range) SD Median (IQR) |
14.33 (6–24) 5.50 14.5 (9.0–18.75) |
12.43 (2–18) 4.33 14.0 (8.5–16.0) |
|
c. Negative Affect mean (range) SD Median (IQR) |
8.25 (3–12) 2.25 9.0 (6.0–10.0) |
5.35 (0–9) 2.28 5.0 (4.0–7.0) |
|
d. Restless/tense behaviour mean (range) SD Median (IQR) |
8.48 (3–12) 2.59 9.0 (6.25–10.0) |
5.13 (0–9) 2.41 5.0 (4.0–7.0) |
|
e. Positive self-image mean (range) SD Median (IQR) |
7.88 (3–11) 1.88 8.0 (6.0–9.0) |
6.23 (0–9) 2.24 6.0 (4.25–8.75) |
|
f. Social Relations mean (range) SD Median (IQR) |
12.03 (7–22) 3.68 11.0 (10.0–13.0) |
11.13 (1–18) 4.79 10.5 (8.25–15.75) |
|
g. Social Isolation (mean (range) SD Median (IQR) |
6.00 (3–11) 1.45 6.0 (5.0–7.0) |
4.60 (10–9) 1.99 5.0 (4.0–6.0) |
|
h. Feeling at home mean (range) SD Median (IQR) |
8.88 (6–14) 2.22 8.0 (7.0–11.0) |
9.68 (1–12) 2.74 11.0 (8.0–12.0) |
|
†EQ 5D-5 L (self) (Mean (range) SD) median (IQR) N |
0.449 (−0.281–0.951) 0.335 0.379 (0.279–0.719) n = 16 |
0.572 (0.027–1.000) 0.327 0.585 (0.34–0.77) n = 13 |
|
†EQ 5D-5 L (proxy) (mean (range) SD) Median (IQR) N |
0.434 (−0.027–0.896) 0.229 0.356 (0.267–0.664) n = 39 |
0.406 (−0.019–0.887) 0.236 0.341 (0.206–0.581) n = 38 |
|
†EQ 5D-5 L Baseline VAS (self) (mean (range) SD) Median (IQR) N |
57.5 (0–100) 31.9 67.5 (32.5–75) n = 14 |
62.9 (10–99) 30.2 75 (30–85) n = 11 |
|
†EQ 5D-5 L Baseline VAS (proxy) (mean (range) SD) Median (IQR) N |
51.6 (2–99) 23.9 57.5 (38.75–66.25) n = 38 |
50.2 (2–90) 27.3 50 (30–70) n = 37 |
| Adverse drug events related to intervention (ADEs) in past three months | 0/40 (0%) | 0/40 (0%) |
#Number of individual medicines which would need to be altered (stopped or started) after researchers with a pharmacy qualification applied STOPPSTART criteria. *NICE (2017) https://www.nice.org.uk/guidance/qs86/resources/falls-in-older-people-pdf-2098911933637, defines a fall as an unintentional or unexpected loss of balance resulting in coming to rest on the floor, the ground or an object below knee level. **Calculation based only on those with any DBI score. †ED5D-5 L index obtained from Devlin et al. [22] on https://euroqol.org, accessed June 2017. ***Average MMSE for the 12 participants who completed the MMSE face to face at both base line and follow-up was 20.5 and 22.1, respectively