Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 11;38:304. doi: 10.1186/s13046-019-1296-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 4 — Overexpression of LEF1 enhances the tumorigenicity of ESCC cells in vivo. a, b Representative tumors from mice injected with 10⁶ LV-LEF1 or LV-GFP ECA109 cells after 6 weeks were presented. Tumor volumes from each group were measured weekly. c Mice were injected with the indicated number of LV-LEF1 or LV-GFP ECA109 cells and tumor incidence in the mouse xenografts were obtained after 28 days. d, e Western blot (d) and Immunohistochemistry (e) analysis the LEF1 and OV6 expression on mouse subcutaneous tumors inoculated after 6 weeks. Scale bar = 50 μm. f-j Indicated number of LV-shLEF1 and LV-GFP ECA109 cells were injected into mice. Tumor volumes (f, g), tumor incidence (h), expression level of LEF1 and OV6 (i, j) were presented. Scale bar = 50 μm