Table 5.
Parasitemia and survival time of infected mice treated with 80% methanol extract of the leaves of Olea europaea in prophylactic test
Groups | % Parasitemia | % Suppression | Survival time (days) |
---|---|---|---|
2% TW80 | 20.95 ± 0.27 | – | 6.33 ± 0.21 |
CQ25 mg/kg | 4.7 ± 0.17 | 77.53a3 | 12.50 ± 0.22a3 |
200 mg/kg | 16.87 ± 0.23 | 19.32a3b3d3e3 | 7.33 ± 0.21a1b3d2e3 |
400 mg/kg | 15.17 ± 0.23 | 27.47a3b3e1 | 8.67 ± 0.21a3b3 |
600 mg/kg | 14.08 ± 0.11 | 32.69a3b3 | 9.17 ± 0.17a3b3 |
Data are expressed as mean ± SEM; n = 6; a, compared to negative control; b, to CQ25 mg/kg; c, to 200 mg/kg; d, to 400 mg/kg; e, to 600 mg/kg; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001; 2% TW80, 2% Tween80; CQ chloroquine