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. 2019 May 27;7(7):e00754. doi: 10.1002/mgg3.754

Table 2.

Basic information of candidate SNPs and minor allele frequency between cases and control participants

SNP rs# Chromosome Alleles A/B Gene(s) MAF p ‐HWE OR (95% CI) p a pb
Case Control
rs12569923 10 C/G IL2RA 0.207 0.193 1.000 1.11 (0.89–1.38) 0.347 0.057
rs791588 10 G/T IL2RA 0.327 0.396 0.925 0.74(0.62–0.89) 0.0014* 0.00023*
rs12722498 10 C/T IL2RA 0.110 0.111 0.649 0.99(0.75–1.31) 0.963 0.1605
rs2281089 22 A/G IL2RB 0.233 0.270 0.909 0.82(0.66–1.00) 0.053 0.0088
rs3218264 22 C/T IL2RB 0.507 0.494 0.531 1.05(0.88–1.25) 0.562 0.0936
rs1573673 22 C/T IL2RB 0.352 0.363 0.100 0.95(0.79–1.14) 0.594 0.099

Abbreviations: Alleles A/B, Minor/major alleles; CI, confidence interval; HWE, Hardy–Weinberg equilibrium; MAF, minor allele frequency; OR, odds ratio; SNP, single‐nucleotide polymorphism.

p a values were calculated using two‐sided chi‐squared test (the major allele of each SNP was a reference allele);

p b values were adjusted by Bonferroni correction.

*

p a ˂ 0.05 indicates statistical significance.

*

p b ˂ 0.008 indicates statistical significance.