Table 2.
SNP rs# | Chromosome | Alleles A/B | Gene(s) | MAF | p ‐HWE | OR (95% CI) | p a | pb | |
---|---|---|---|---|---|---|---|---|---|
Case | Control | ||||||||
rs12569923 | 10 | C/G | IL2RA | 0.207 | 0.193 | 1.000 | 1.11 (0.89–1.38) | 0.347 | 0.057 |
rs791588 | 10 | G/T | IL2RA | 0.327 | 0.396 | 0.925 | 0.74(0.62–0.89) | 0.0014* | 0.00023* |
rs12722498 | 10 | C/T | IL2RA | 0.110 | 0.111 | 0.649 | 0.99(0.75–1.31) | 0.963 | 0.1605 |
rs2281089 | 22 | A/G | IL2RB | 0.233 | 0.270 | 0.909 | 0.82(0.66–1.00) | 0.053 | 0.0088 |
rs3218264 | 22 | C/T | IL2RB | 0.507 | 0.494 | 0.531 | 1.05(0.88–1.25) | 0.562 | 0.0936 |
rs1573673 | 22 | C/T | IL2RB | 0.352 | 0.363 | 0.100 | 0.95(0.79–1.14) | 0.594 | 0.099 |
Abbreviations: Alleles A/B, Minor/major alleles; CI, confidence interval; HWE, Hardy–Weinberg equilibrium; MAF, minor allele frequency; OR, odds ratio; SNP, single‐nucleotide polymorphism.
p a values were calculated using two‐sided chi‐squared test (the major allele of each SNP was a reference allele);
p b values were adjusted by Bonferroni correction.
p a ˂ 0.05 indicates statistical significance.
p b ˂ 0.008 indicates statistical significance.