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Biogenesis and destination of exosomes inside and outside the cell [based on (4,5,7,8,86)]. Nanovesicles in the multivesicular body can be transferred to lysosomes or be released from the cell to enter into blood vessels or fuse with neighboring cells. When entering the target cells, the exosome cargo can exert a different biological effect, resulting in changes in cell physiology for example-reprogramming it into a cancer cell.
