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. 2019 Jun 6;20(2):931–938. doi: 10.3892/mmr.2019.10358

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Effects of RNF10 on vascular remodeling in diabetic rats with carotid artery injury. RNF10 as a key factor attenuated vascular remodeling via suppressing inflammatory responses, hyperproliferation and inhibitory apoptosis. RNF10, RING finger protein 10; VSMCs, vascular smooth muscle cells; TNF-α, tumor necrosis factor α; MCP-1, monocyte chemotactic protein 1; NF-κB, nuclear factor-κ-gene binding; Bax, B-cell CLL/lymphoma 2 associated X protein; Bcl-2, B-cell CLL/lymphoma 2; CDK4, cyclin dependent kinase 4.