Table IV.

GO terms and KEGG pathways for the critical DEGs in the gene co-expression network.

Term	Count	P-value
Biological process
GO:0006952-defense response	17	6.710×10−4
GO:0070271-protein complex biogenesis	14	2.379×10−3
GO:0006461-protein complex assembly	14	2.379×10−3
GO:0006954-inflammatory response	10	6.995×10−3
GO:0065003-macromolecular complex assembly	15	9.548×10−3
GO:0007267-cell-cell signaling	14	9.895×10−3
GO:0006955-immune response	15	1.289×10−2
GO:0043933-macromolecular complex subunit organization	15	1.618×10−2
GO:0042127-regulation of cell proliferation	15	3.508×10−2
GO:0010033-response to organic substance	14	3.794×10−2
Cellular component
GO:0005615-extracellular space	22	9.670×10−6
GO:0044421-extracellular region part	24	1.680×10−4
GO:0005576-extracellular region	37	7.410×10−4
GO:0000267-cell fraction	21	9.733×10−3
GO:0044459-plasma membrane part	35	1.210×10−2
GO:0005624-membrane fraction	16	2.361×10−2
GO:0005886-plasma membrane	52	2.390×10−2
GO:0005626-insoluble fraction	16	3.132×10−2
GO:0031988-membrane-bounded vesicle	12	3.805×10−2
GO:0005887-integral to plasma membrane	20	4.399×10−2
GO:0046983-protein dimerization activity	12	3.398×10−2
GO:0005509-calcium ion binding	17	4.100×10−2
GO:0042802-identical protein binding	13	4.578×10−2
KEGG pathway
hsa04142: Lysosome	6	1.733×10−3
hsa04060: Cytokine-cytokine receptor interaction	9	1.914×10−3
hsa04115: p53 signaling pathway	4	5.762×10−3
hsa04062: Chemokine signaling pathway	6	9.418×10−3
hsa05200: Pathways in cancer	8	1.309×10−2
hsa04512: ECM-receptor interaction	3	2.978×10−2
hsa04110: Cell cycle	3	4.860×10−2
hsa04510: Focal adhesion	4	4.878×10−2

GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.