Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 3;20(2):995–1006. doi: 10.3892/mmr.2019.10326

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Dai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — lncRNA CASC2 was upregulated by berberine treatment in CRC. A-F. RT-qPCR analysis of the six indicated lncRNAs, (A) LINC01018, (B) CASC2, (C) LOC728431, (D) LOC33817, (E) HAR1B, (F) MALAT1, in HT29 cells cultured with berberine-containing medium or berberine-free medium. (G) lncRNA CASC2 expression was measured using RT-qPCR in the indicated cell lines. *P<0.05 vs. FHC cells. (H) lncRNA CASC2 level was detected via RT-qPCR in paired CRC tissues and adjacent non-tumor tissues obtained from patients with CRC. The expression of lncRNA CASC2 was significantly downregulated in primary CRC tissues when compared with noncancerous tissues. (I) lncRNA CASC2 level was increased in HT29 cells following treatment with berberine at increasing concentrations for 48 h. *P<0.05 vs. control cells. lncRNA, long non-coding RNA; CASC2, cancer susceptibility 2; CRC, colorectal cancer; RT-qPCR, reverse-transcription quantitative PC; LINC01018, long intergenic non-protein coding RNA 1018; LOC728431, long intergenic non-protein coding RNA 1137; MALAT1, metastasis associated lung adenocarcinoma transcript 1.