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View full-text article in PMC

. 2019 Jul 5;7:161. doi: 10.3389/fbioe.2019.00161

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Copyright © 2019 Kargozar, Montazerian, Fiume and Baino.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Micro-CT evaluation of bone regeneration in the rat tibia defects after implantation of PMMA and 30Sr-BG/PMMA composite cements. The 3D reconstructed sagittal images of the area surrounding the cement implants show new bone formation around the cement-host bone interface at (A) 8 and (B) 12 weeks (area outlined in red); (C) BV/TV (bone volume/total volume) in the defects implanted with 30SrBG/PMMA composite cement for different post-implantation times. Values are presented as mean ± s.d.; n = 3. *Significant difference between groups (p < 0.05) [Adapted from Cui et al. (2017) with permission from The Royal Society].