Table 2.
Effect of berberine on the anthropometric variables, biochemical and inflammatory biomarkers in diclofenac-induced acute kidney injury
| Variable | AKI (n=10) | Berberine (n=10) | P |
|---|---|---|---|
| BMI (g/cm2) | 0.64±0.03 | 0.54±0.01 | 0.0003* |
| Blood urea (mg/dL) | 70.50±12.53 | 71.62±10.86 | 0.85 |
| Serum creatinine (mg/dL) | 1.52±0.49 | 1.23±0.43 | 0.22 |
| eGFR (ml/min/1.73) | 7.59±1.7 | 9.55±3.78 | 0.20 |
| KIM-1 (pg/mL) | 269.03±29.61 | 89.00±29.63 | 0.0001* |
| NGAL (pg/mL) | 18.76±4.13 | 18.13±2.95 | 0.73 |
*P<0.01. BMI: Body mass index, KIM-1: Kidney injury molecule-1, NGAL: Neutrophil gelatinase-associated lipocalin, AKI: Acute kidney injury, eGFR: Estimated glomerular filtration rate