Table 1.
Baseline Demographic and Clinical Characteristics
| Variablea | Placebo (n = 27) |
O3FA (n = 21) |
Total (N=48) |
P Valueb |
|---|---|---|---|---|
| Age, y | 16.34 (1.981) | 15.68 (2.190) | 16.05 (2.079) | .28 |
| Sex | .88 | |||
| Male | 11 (40.7) | 9 (42.9) | 20 (41.7) | |
| Female | 16 (59.3) | 12 (57.1) | 28 (58.3) | |
| Race/ethnicity | .13 | |||
| White | 11 (40.7) | 13 (61.9) | 24 (50.0) | |
| Hispanic | 6 (22.2) | 7 (33.3) | 13 (27.1) | |
| African-American | 6 (22.2) | 1 (4.8) | 7 (14.6) | |
| Asian | 2 (7.4) | 0 (0.0) | 2 (4.2) | |
| Other | 2 (7.4) | 0 (0.0) | 2 (4.2) | |
| Adjunctive therapy | .58 | |||
| None | 20 (74.1) | 13 (61.9) | 33 (68.8) | |
| Cognitive behavioral therapy | 1 (3.7) | 2 (9.5) | 3 (6.2) | |
| Other therapy | 6 (22.2) | 6 (28.6) | 12 (25.0) | |
| Current episode duration, | 28.6 (20.2) | 15.3 (8.6) | 22.5 (17.2) | <.01 |
| moc | ||||
| Total number of episodes | .05 | |||
| 1 | 20 (74.1) | 20 (95.2) | 40 (83.3) | |
| 2 | 7 (25.9) | 1 (4.8) | 8 (16.7) | |
| History of suicide attempt | 5 (18.5) | 1 (4.8) | 6 (12.5) | .15 |
| Current comorbid disorders | ||||
| Anxiety | 13 (48.1) | 11 (52.4) | 24 (50.0) | .77 |
| ADHD | 6 (22.2) | 2 (9.5) | 8 (16.7) | .24 |
| Oppositional defiant disorder | 1 (3.7) | 1 (4.8) | 2 (4.2) | .86 |
a
Summary statistics presented are mean (standard deviation) for continuous or frequency (%) for categorical variables.
b
P value according to t test for continuous variables or χ2 test for categorical variables.
c
Data missing for 2 participants assigned to placebo.
Abbreviations: ADHD = attention-deficit/hyperactivity disorder, O3FA = omega-3 fatty acids.