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. 2019 Jun 6;20(2):1333–1342. doi: 10.3892/mmr.2019.10363

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Copyright: © Xia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Lidocaine upregulates the expression of miR-520a-3p in RB cells. (A) Expression of miR-520a-3p in RB and normal adjacent tissues. n=30/group. Data are presented as the mean ± standard deviation. **P<0.01 vs. normal tissues. (B) Expression of miR-520a-3p in RB cell lines and the retinal pigment epithelial cell line ARPE-19. *P<0.05, **P<0.01 vs. ARPE-19. (C) Expression of miR-520a-3p in Y79 cells following treatment with 500 µM lidocaine for 24 h. **P<0.01 vs. control. Data are presented as the mean ± standard deviation of three independent experiments performed in triplicate. miR-520a-3p, microRNA-520a-3p; RB, retinoblastoma.