Table IV.
GO analysis of selected module-associated DEGs.
| ID | GO Terms | Ontology | q-value | Genes |
|---|---|---|---|---|
| GO:0000819 | Sister chromatid segregation | BP | 5.54×10−13 | BUB1B/CCNB1/CDC6/CENPA/DLGAP5/ERCC6L/MAD2L1/NUF2/SPC25/TOP2A/TRIP13/TTK/UBE2C |
| GO:0007088 | Regulation of mitotic nuclear division | BP | 8.77×10−12 | ANLN/AURKA/BUB1B/CCNB1/CDC6/CHEK1/DLGAP5/MAD2L1/TRIP13/TTK/UBE2C |
| GO:0098813 | Nuclear chromosome | BP | 1.24×10−11 segregation | BUB1B/CCNB1/CDC6/CENPA/DLGAP5/ERCC6L/MAD2L1/NUF2/SPC25/TOP2A/TRIP13/TTK/UBE2C |
| GO:0051304 | Chromosome separation | BP | 1.37×10−11 | BUB1B/CCNB1/CDC6/DLGAP5/MAD2L1/TOP2A/TRIP13/TTK/UBE2C |
| GO:0030071 | Regulation of mitotic metaphase/anaphase transition | BP | 1.46×10−11 | BUB1B/CCNB1/CDC6/DLGAP5/MAD2L1/TRIP13/TTK/UBE2C |
| GO:0000793 | Condensed chromosome | CC | 2.53×10−10 | AURKA/BUB1B/CCNB1/CENPA/CHEK1/ERCC6L/MAD2L1/NUF2/SKA3/SPC25/TOP2A |
| GO:0000779 | Condensed chromosome/centromeric region | CC | 5.40×10−10 | AURKA/BUB1B/CCNB1/CENPA/ERCC6L/MAD2L1/NUF2/SKA3/SPC25 |
| GO:0000775 | Chromosome/centromeric region | CC | 1.59×10−9 | AURKA/BUB1B/CCNB1/CENPA/ERCC6L/MAD2L1/NUF2/SKA3/SPC25/TTK |
| GO:0000776 | Kinetochore | CC | 1.80×10−9 | BUB1B/CCNB1/CENPA/ERCC6L/MAD2L1/NUF2/SKA3/SPC25/TTK |
| GO:0000777 | Condensed chromosome kinetochore | CC | 8.17×10−9 | BUB1B/CCNB1/CENPA/ERCC6L/MAD2L1/NUF2/SKA3/SPC25 |
| GO:0008009 | Chemokine activity | MF | 1.41×10−9 | CCL19/CCL28/CXCL1/CXCL12/CXCL3/CXCL5/CXCL8 |
| GO:0042379 | Chemokine receptor binding | MF | 8.09×10−9 | CCL19/CCL28/CXCL1/CXCL12/CXCL3/CXCL5/CXCL8 |
| GO:0045236 | CXCR chemokine receptor binding | MF | 1.46×10−8 | CXCL1/CXCL12/CXCL3/CXCL5/CXCL8 |
| GO:0035173 | Histone kinase activity | MF | 1.99×10−4 | AURKA/CCNB1/CHEK1 |
Adjusted P<0.05 was considered as significanct. DEGs, differentially expressed genes; CRC, colorectal cancer; q-value, adjusted P-value; GO, Gene Ontology; BP, biological process; CC, cellular component; MF, molecular function.