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. 2019 Jun 20;20(2):1621–1628. doi: 10.3892/mmr.2019.10407

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Copyright: © Ma et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Tan IIA treatment ameliorates inflammatory cytokine upregulation in LPS-stimulated RAW 264.7 cells. The cells were treated with DMSO, LPS (1 µg/ml) or LPS (1 µg/ml) + Tan IIA (10 µM) for 24 h. (A-D) ELISA assays were utilized to examine the concentration of four inflammatory cytokines: (A) TNF-α, (B) MCP-1, (C) IL-6 and (D) IL-1β in the RAW 264.7 cells. Results are presented as the mean ± standard deviation. *P<0.05 vs. the indicated control. Tan IIA, tanshinone IIA; LPS, lipopolysaccharide; MCP-1, monocyte chemoattractant protein-1; TNFα, tumor necrosis factor α; IL, interleukin.