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. 2019 Jun 20;20(2):1621–1628. doi: 10.3892/mmr.2019.10407

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Copyright: © Ma et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Tan IIA restores the proliferation and migration capacity of LPS-stimulated RAW 264.7 cells. (A) Proliferation rates of DMSO, LPS or LPS+Tan IIA-treated RAW 264.7 cells were determined by CCK-8 assay. Optical density (OD)450 values at the indicated time points are presented as the mean ± standard deviation from six independent experiments. *P<0.05 vs. the indicated control. (B) Cell migration capacities of DMSO, LPS or LPS+Tan IIA-treated RAW 264.7 cells were assessed by Transwell assay. Representative images are shown at the top of the histogram. Four random microscopic fields (magnification, ×100) were used for cell counting (bottom histogram). Data are presented as the mean ± standard deviation from three independent experiments. *P<0.05 vs. the indicated control. Tan IIA, tanshinone IIA; LPS, lipopolysaccharide.