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. 2019 Jun 25;20(2):1593–1604. doi: 10.3892/mmr.2019.10423

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Trajectory of guinea pig movement in the Morris water maze. (A) In the hidden platform experiment, the guinea pigs began to search for the platform in two manners: Random searching and circular movement. (B) As the amount of training received increased, the guinea pigs began to search near the platform location with increased tendency, or swim in direct lines to the platform; however, animals in the D-gal did not exhibit similar changes in behavior. (C) In the search platform experiment, animals in the D-gal group exhibited a notably lesser preference for the former location of the platform compared with the NS and control groups. NS, normal saline; D-gal, D-galactose.