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. 2019 Jun 13;20(2):1826–1836. doi: 10.3892/mmr.2019.10382

Figure 1.

Figure 1.

Upregulation of NLRP3 inflammasome mRNA levels in PBMCs in patients with SAP and AMI, compared with non-CHD controls. (A) PBMCs were isolated from peripheral blood and the positive rate of CD14 was calculated to be ≥95% of PBMCs by flow cytometry. RT-PCR assays were performed to quantify the mRNA levels of (B) NLRP3, (C) ASC and (D) caspase-1 in PBMCs of each group. *P<0.05; **P<0.01. NLRP3, nucleotide-binding oligomerization domain, leucine rich repeat, and pyrin domain-containing protein 3; PBMCs, peripheral blood monocytes; SAP, stable angina pectoris; AMI, acute myocardial infarction; CHD, coronary heart disease; ASC, apoptosis-associated speck-like protein containing a CARD.