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. 2019 Jun 20;20(2):1797–1807. doi: 10.3892/mmr.2019.10408

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — MKK3 and miR-21 expression levels are dysregulated in melanoma tissues. (A) RT-qPCR analysis of MKK3 mRNA levels in 15 pairs of melanoma tissues and adjacent normal tissues. (B) Western blot analysis of MKK3 protein levels in 15 pairs of melanoma tissues and adjacent normal tissues. The band intensity was determined to quantify protein expression levels. MKK3 and miR-21 expression levels are dysregulated in melanoma tissues. (C) RT-qPCR analysis of miR-21 levels in 15 pairs of melanoma tissues and adjacent normal tissues. The results are presented as the mean ± standard deviation of three replicates per tissue sample. MKK3, mitogen-activated protein kinase kinase 3; miR-21, microRNA-21; RT-qPCR, reverse transcription-quantitative PCR; P, patient.

Figure 1. — MKK3 and miR-21 expression levels are dysregulated in melanoma tissues. (A) RT-qPCR analysis of MKK3 mRNA levels in 15 pairs of melanoma tissues and adjacent normal tissues. (B) Western blot analysis of MKK3 protein levels in 15 pairs of melanoma tissues and adjacent normal tissues. The band intensity was determined to quantify protein expression levels. MKK3 and miR-21 expression levels are dysregulated in melanoma tissues. (C) RT-qPCR analysis of miR-21 levels in 15 pairs of melanoma tissues and adjacent normal tissues. The results are presented as the mean ± standard deviation of three replicates per tissue sample. MKK3, mitogen-activated protein kinase kinase 3; miR-21, microRNA-21; RT-qPCR, reverse transcription-quantitative PCR; P, patient.