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. 2019 Jun 20;20(2):1797–1807. doi: 10.3892/mmr.2019.10408

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — miR-21 inhibits, and MKK3 promotes melanoma cell migration and invasion. (A) Migratory ability of A2058 cells was analyzed using a Transwell assay. (B) Invasive ability of cells was compared using a Matrigel assay. Scale bar, 20 µm (magnification, ×200). **P<0.01. The results are presented as the mean ± standard deviation of at least three independent experiments performed in triplicate. MKK3, mitogen-activated protein kinase kinase 3; miR-21, microRNA-21; NC, negative control; siRNA, small interfering RNA.