Table 2.
Mean AC values
| Stages of pregnancy | Mean AC (mg/[mg/L]) | Percentage changesa | SD | Number of patients | Number of samples | p‐value |
|---|---|---|---|---|---|---|
| Prepregnancy | 40.5 | 12.8 | 7 | 7 | ||
| 1st trimester | 73.9 | 82.5 | 36.1 | 10 | 13 | 0.0343 |
| 2nd trimester | 122.8 | 203.2 | 53.2 | 12 | 25 | 0.0010 |
| 3rd trimester | 120.3 | 197.0 | 66.0 | 12 | 28 | 0.0061 |
| PP1M | 83.6 | 106.4 | 55.9 | 8 | 8 | 0.0683 |
| PP2M | 33.6 | −17.0 | 17.6 | 5 | 5 | 0.4495 |
Abbreviations: AC, apparent clearance; PP1M, PP2M, first and second month postpartum, respectively; SD, standard deviation.
a
Percentage change compared with values before pregnancy.