Table 4.
Proportional Hazard Ratios and 95% Confidence Intervals of Estimated Effects of Tertiles of MIND, Mediterranean, and DASH Diet Scores on Time to Incident Mobility Disability on Rosow–Breslau Scale (n = 515) in Memory and Aging Project Participants Over a Mean 3.8 Years of Follow-up, 2004–2017
| Score Range | No. of Events/N | Model 1† | Model 2‡ | Model 3§ | |
|---|---|---|---|---|---|
| MIND Diet Score | |||||
| T1 | 3.0–7.0 | 184/229 | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| T2 | 7.5–8.5 | 103/156 | 0.69 (0.54–0.88) | 0.74 (0.58–0.96) | 0.69 (0.56–0.94) |
| T3 | 9.0–13.0 | 94/130 | 0.78 (0.60–1.01) | 0.83 (0.64–1.08) | 0.80 (0.61–1.05) |
| p trend | .02 | .07 | .04 | ||
| Mediterranean Diet Score | |||||
| T1 | 18–30 | 149/183 | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| T2 | 31–34 | 116/163 | 0.85 (0.66–1.10) | 0.87 (0.67–1.13) | 0.87 (0.66–1.13) |
| T3 | 35–46 | 116/169 | 0.77 (0.59–1.00) | 0.81 (0.62–1.07) | 0.82 (0.62–1.08) |
| p trend | .05 | .15 | .16 | ||
| DASH Diet Score | |||||
| T1 | 3.0–3.5 | 168/215 | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| T2 | 4.0–4.5 | 108/138 | 0.90 (0.70–1.15) | 0.93 (0.73–1.20) | 0.93 (0.71–1.20) |
| T3 | 5.0–8.5 | 105/162 | 0.70 (0.55–0.91) | 0.71 (0.55–0.92) | 0.76 (0.58–0.99) |
| p trend | .01 | .01 | .05 | ||
Notes: Cox-Proportional hazard model was used. DASH = Dietary Approaches to Stop Hypertension; MIND = Mediterranean–DASH Diet Intervention for Neurodegenerative Delay; T1 = tertile 1; T2 = tertile 2; T3 = tertile 3.
†Model 1 adjusted for age, sex, education, smoking, physical activity, and total calories.
‡Model 2 adjusted for Model 1 + body mass index + depressive symptoms.
§Model 3 adjusted for Model 1 + cardiovascular conditions (including diabetes, hypertension, stroke, and myocardial infarction).