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. 2019 Mar 15;74(8):1180–1188. doi: 10.1093/gerona/glz067

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© The Author(s) 2019. Published by Oxford University Press on behalf of The Gerontological Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Yolk accumulation results from continued vitellogenesis and cessation of egg laying. (A) Cartoon showing faucet and sink model. (B) Age changes in vitellogenin accumulation (left) and accumulation rate (right), summed data from four trials. Top, YP170; bottom, YP115. Data shown with and without adjustment for age changes in intestinal volume. (C) Combined figure showing yolk protein (YP) adjusted accumulation and accumulation rate, and other age changes. Left, with YP170; right, with YP115. (D) Mating of N2 hermaphrodites with males (fog-2) reduces YP170 accumulation. Left, total accumulation. Right, accumulation rate. (E) YP170 accumulation in spermless fog-2(q71) females. Left, total accumulation. Right, accumulation rate. (D and E) Summed data from three trials, age-matched comparison. Data are mean ± SEM, *p < .05, **p < .01, ***p < .001.