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. 2019 Mar 15;74(8):1180–1188. doi: 10.1093/gerona/glz067

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© The Author(s) 2019. Published by Oxford University Press on behalf of The Gerontological Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — YP170 production accelerates intestinal atrophy and shortens life span. (A) Effect of vit RNAi on intestinal atrophy. Left, microscope images, scale bars, 10 μm. Right, quantitation. (B) Effect of vit RNAi on life span. Bar graphs depicting mean ± SEM of life spans for individual trials; p, log-rank test. (C) Effect of vit RNAi on yolk pool accumulation. Left, microscope images, scale bars, 10 μm. Right, quantitation (A and C). Filled arrowheads, intestine. Open arrowheads, PLPs. Data are mean ± SEM, age-matched comparison, *p < 0.05, ***p < 0.001.