Table 1. Comparative effects of olive and palm products and omega-3 fish oil.
| Time (h) | LPSOmg | LPSOlv | LPSExOlv | LPSEx | LPSPal | |
|---|---|---|---|---|---|---|
| TBARS | 0 | 10.3 ± 1.7 | 9.90 ± 1.7 | 9.7 ± 2.2 | 7.3 ± 3.5 | 8 ± 1.9 |
| 24 | 53.2 ± 10.3 | 76.5 ± 20 | 80.7 ± 19 | 134.3 ± 18.4* | 102.6 ± 24.7* | |
| 48 | 58.5 ± 13.2 | 82.3 ± 26.3 | 86.8 ± 23.5 | 164.9 ± 26.4** | 130.1 ± 28.3** | |
| IL-6 | 0 | 8.69 ± 1.0 | 9.99 ± 1.04 | 10.0 ± 1.5 | 10.1 ± 1.8 | 9.1 ± 1.4 |
| 17 | 76.3 ± 39.4 | 92.7 ± 31.5 | 121.8 ± 45.8 | 202 ± 51.8* | 194.2 ± 62.4* | |
| 48 | 14.2 ± 4.7 | 12.1 ± 4.5 | 17.9 ± 13.3** | 27.2 ± 5.5** | 17.2 ± 3.9** | |
| IL-1β | 0 | 29 ± 3 | 32 ± 4 | 32 ± 5 | 37 ± 2 | 29 ± 8 |
| 17 | 139 ± 29 | 166 ± 57 | 174 ± 77 | 404 ± 125* | 256 ± 140* | |
| 48 | 154 ± 59 | 198 ± 80 | 205 ± 114 | 439 ± 82** | 285 ± 103** |
Notes:
Quantification of thiobarbituric acid reactive substances (TBARS), interleukin 6 (IL-6) levels, and interleukin 1β (IL-1β) levels in septic rats treated with an ethanolic extract of Brazilian olive leaf (LPSEx), Brazilian olive oil (LPSOlv), ethanolic extract of Brazilian olive leaf + Brazilian olive oil (LPSExOlv), palm oil (LPSPal), and omega-3 fish oil (LPSOmg). Data are reported as means ± SD. The significance level for the null hypothesis was set at 5% (p < 0.05).
*
For all groups at 17 or 24 h compared to the LPSOmg group at 17 or 24 h.
**
For all groups at 48 h compared to the LPSOmg group at 48 h (simple linear regression analysis followed by Bonferroni post hoc test).