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. 2019 Jul 8;12:1047–1056. doi: 10.2147/DMSO.S179793

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© 2019 Urakami.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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Expression of maturity-onset diabetes of the young (MODY)-causative genes in pancreatic β-cells and mechanism of insulin secretion.

Abbreviations: ATP, adenosine triphosphate; cAMP, cyclic adenosine 3ʹ,5ʹ-monophosphate; PKA, protein kinase A; Epac, exchange protein directly activated by cAMP; K_ATP channel, ATP-sensitive potassium channel; VDCC, voltage-dependent calcium channel; GCK, glucokinase; HNF4α, hepatocyte nuclear factor 4α; HNF1α, hepatocyte nuclear factor 1α; PDX1, pancreatic and duodenal homeobox 1; HNF1β, hepatocyte nuclear factor 1β; NEUROD1, neurogenic differentiation 1.