Table 2.
Associations of continuous eGFR with quantitative gait markers
| Gait Marker | eGFR ≥60 (n=196) | eGFR <60 (n=134) |
|---|---|---|
| Coefficient (95% CI) | Coefficient (95% CI) | |
| Age and sex adjustment, per 10 ml/min per 1.73 m2 higher eGFRa | ||
| Speed, cm/s | 0.3 (−2.3 to 2.9) | 3.6 (0.8 to 6.3) |
| Stride length, cm | −0.2 (−2.4 to 1.9) | 3.9 (1.6 to 6.1) |
| Swing, % | −0.01 (−0.4 to 0.3) | 0.7 (0.3 to 1.1) |
| Double support, % | −0.1 (−0.8 to 0.5) | −1.1 (−1.8 to −0.4) |
| Stride length variability, SD | −0.1 (−0.3 to 0.2) | 0.1 (−0.2 to 0.3) |
| Cadence, steps/min | 0.4 (−1.0 to 1.9) | 0.4 (−1.2 to 1.9) |
| Multivariable model, per 10 ml/min per 1.73 m2 higher eGFRb | ||
| Speed, cm/s | −0.1 (−2.6 to 2.4) | 3.3 (0.6 to 5.9) |
| Stride length, cm | −0.7 (−2.7 to 1.4) | 3.6 (1.4 to 5.8) |
| Swing, % | −0.2 (−0.5 to 0.1) | 0.7 (0.3 to 1.0) |
| Double support, % | 0.2 (−0.4 to 0.8) | −1.1 (−1.7 to −0.5) |
| Stride length variability, SD | −0.1 (−0.3 to 0.1) | 0.05 (−0.2 to 0.3) |
| Cadence, steps/min | 0.4 (−1.0 to 1.8) | 0.4 (−1.1 to 1.9) |
95% CI, 95% confidence interval.
a
Linear splines for eGFR constructed with knot placed at 60 ml/min per 1.73 m2.
b
Multivariable model adjusted for age, sex, race, education, body-mass index, neuropathy, and number of comorbidities.