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. 2019 Jun 18;25(7):408–422. doi: 10.1093/molehr/gaz028

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© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

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Regulatory networks representing the effects of each individual stimulus. RNEA was performed and significant subnetworks were identified in samples treated by A. P4, B. FSK (cAMP), and C. IL-1 based on gene expression alterations compared to control. Nodes (genes and TFs) are colored based on . Edges (regulatory interactions) and node outlines are colored based on occurrence in the three shown networks. cutoffs used for significance in the RNEA function were 1.5 for P4 and IL-1 and 1.75 for FSK. Visualization was performed using Cytoscape. See Supplementary Files I–III for full RNEA networks for P4, FSK, and IL-1, respectively.

Inline graphic — Regulatory networks representing the effects of each individual stimulus. RNEA was performed and significant subnetworks were identified in samples treated by A. P4, B. FSK (cAMP), and C. IL-1 based on gene expression alterations compared to control. Nodes (genes and TFs) are colored based on . Edges (regulatory interactions) and node outlines are colored based on occurrence in the three shown networks. cutoffs used for significance in the RNEA function were 1.5 for P4 and IL-1 and 1.75 for FSK. Visualization was performed using Cytoscape. See Supplementary Files I–III for full RNEA networks for P4, FSK, and IL-1, respectively.