Table 2.

Differential miRNA expression between controls (n=8) and all stroke cases (n=16). Known disease associations are listed.

miRNA	P-value	Log FC	Fold change	Regulation	Previous Associations
hsa-miR-145–5p	0.0398	0.399	1.319	Upregulated	Ischemic Stroke [3–5,7,8]
hsa-miR-943	0.0437	0.234	1.176	Upregulated	Cancer [2], Ischemic Stroke [5,7]
hsa-miR-664a-3p	0.0247	0.227	1.170	Upregulated	Cancer [9]
hsa-miR-2116–5p	0.0437	−0.179	0.883	Downregulated	Cancer [12]
hsa-miR-4531	0.0428	−0.194	0.874	Downregulated	None
hsa-miR-4764–5p	0.0419	−0.251	0.840	Downregulated	Rheumatoid Arthritis [14]
hsa-miR-647	0.0247	−0.283	0.822	Downregulated	Cancer [11]
hsa-miR-4742–3p	0.0383	−0.289	0.818	Downregulated	Autism [10]
hsa-let-7e-5p	0.0398	−0.309	0.807	Downregulated	Ischemic Stroke [3–5]
hsa-miR-5584–3p	0.0247	−0.312	0.806	Downregulated	None
hsa-miR-4756–3p	0.023	−0.333	0.794	Downregulated	None
hsa-miR-4709–3p	0.023	−0.372	0.773	Downregulated	Autism [10]
hsa-miR-5187–3p	0.0113	−0.426	0.744	Downregulated	Endometriosis [15]
hsa-miR-1273e	0.0113	−0.426	0.744	Downregulated	Ischemic Stroke [5]