Table 1:

Baseline Characteristics

	Switch from EFV+FTC/TDF to:
	EVG/c/FTC/TDF (n=10)	RAL+FTC/TDF (n=10)	p-value	All participants (n=20)
No. of participants	10.0	10.0	-	20.0
Age (mean)	46.5 (9.0)	47.9 (9.9)	0.7	47.2 (9.2)
Male gender (%)	90	60	-	75
CD4 T cell (mean)	657 (187)	709 (280.5)	0.6	683 (234)
HIV-1 RNA <20 copies/ml (%)	80.0	80.0	-	80.0
On ART (%)	100	100	-	100
Creatinine (mean)	0.9 (0.2)	0.8 (0.2)	0.4	0.9 (0.2)
Cholesterol (mean)	178.8 (24.2)	200.9 (37.0)	0.1	190.0 (32.5)
% on statin	10	30	-	20
ALT (mean)	26.2 (15.2)	28.6 (15.1)	0.6	27.4 (14.8)
EFV plasma conc (mcg/ml)*	2.3 (0.9)	3.9 (2.3)	0.1	3.1 (1.9)
8-OH EFV conc	0.6 (0.4)	0.5 (0.4)	0.8	0.5 (0.4)
7-OH EFV conc	0 (0)	0.01 (0.01)	0.1	0.01 (0.01)
Post- EFV plasma conc (mcg/ml)	0.02 (0.05)	0 (0)	0.4	0.4 (0.7)
Post 8-OH EFV conc	0 (0)	0 (0)	0.3	0 (0)
Post 7-OH EFV conc	0 (0)	0.01 (0.01)	0.05	0 (0)

^*mean (stdv)