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Effect of TBT exposure on mRNA expression in pre-luteinized and luteinized primary ovine theca cells. mRNA expression (mean ± SEM) of steroidogenic enzymes HSD3β1, HSD17β1 and CYP11A1 and transport protein (StAR) in pre-luteinized (A) and luteinized (B) ovine primary theca cells exposed to 1 ng/ml TBT (gray bars), 10 ng/ml TBT (closed bars) or vehicle (control group; open bars). Asterisks denote differences among treatments (P < 0.05). N=3 primary cultured cell lines per group.
