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Effect of TBT exposure on mRNA (ABCA1 and StAR; A) and protein (ABCA1; B) expression (mean ± SEM) in pre-luteinized ovine primary theca cells exposed to 1 ng/ml TBT (gray bars), 10 ng/ml TBT (closed bars) and / or RXR antagonist (UVI3003; 0.05, 2, 4 and 8 μM) or vehicle (control group; open bars). Asterisks denote differences among treatments (P < 0.05). N=3 primary cultured cell lines per group.
